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Document ID (ISN)66644
CIS number 96-729
ISSN - Serial title 0160-2748 - Neurotoxicology
Year 1994
Convention or series no.
Author(s) Ruijten M.W.M.M., Hooisma J., Brons J.T., Habets C.E.P., Emmen H.H., Muijser H.
Title Neurobehavioral effects of long-term exposure to xylene and mixed organic solvents in shipyard spray painters
Bibliographic information Fall 1994, Vol.15, No.3, p.613-620. 33 ref.
Abstract A cross-sectional study was performed in shipyard painters exposed to organic solvents and age-matched referents. The work duties of the painters mainly involved spray painting with solvent-based paints containing > 50% xylene. Results indicate that complaints regarding mood changes, equilibrium and fatigue were more severe in painters than in controls, but were not related to the estimated life-time exposure index. Decreased nerve function was observed in the lower extremities and to some extent in the upper extremities. The refractory period appeared to be a sensitive parameter in motor nerves. Most neurophysiological parameters investigated were significantly related to the exposure index. Behavioural testing revealed impairment of simple visuo-motor performance and complex perceptual coding. A relationship between effects on perceptual coding and the exposure index was also demonstrated.
Descriptors (primary) symptoms; shipyards; paint spraying; neuropsychic effects; xylene; psychological tests; long-term exposure; organic solvents
Descriptors (secondary) fatigue; perceptual-motor performance tests; learning performance tests; cross-sectional study
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Other equipment and plant
Broad subject area(s) Chemical safety
Browse category(ies) Surface treatment
Diseases of the nervous system
Aromatic hydrocarbons
Shipbuliding and ship repair