|Document ID (ISN)||66637|
|ISSN - Serial title
||0273-2300 - Regulatory Toxicology and Pharmacology
|Convention or series no.
||Viren J.R., Silvers A.
||Unit risk estimates for airborne arsenic exposure: An updated view based on recent data from two copper smelter cohorts
||Oct. 1994, Vol.20, No.2, p.125-138. Illus. 20 ref.
||The current unit risk for chronic lifetime exposure to airborne arsenic 4.29 x 10-3, was established by the US EPA in 1984. Using updated results from a cohort mortality study on Tacoma, Washington, smelter workers and recent findings from a cohort study of 3619 Swedish smelter workers, new unit risk estimates were developed for the respective cohorts. Methods were analogous to those used by the EPA in 1984, and all estimates were derived under an absolute risk model. A new unit risk 1.28 x 10-3, was estimated for the Tacoma smelter cohort which was a factor of five less than the EPA's earlier estimate, and a direct result of radically revised exposure estimates. A unit risk of 0.89 x 10-3 was estimated from the Swedish study. Pooling these new risk estimates with the EPA's earlier estimates yielded a composite unit risk of 1.43 x 10-3. Based on this estimate, the present unit risk may overestimate the effects of airborne arsenic by a factor of 3.
||airborne dust; arsenic; long-term exposure; exposure evaluation; permissible levels
||Sweden; USA; lung cancer; Washington; determination of exposure limits; smelting plants; cohort study
||D - Periodical articles
|Country / State or Province||USA|
||Toxic and dangerous substances
|Broad subject area(s)
Arsenic and compounds
Occupational exposure limits