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Document ID (ISN)66508
CIS number 96-859
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1995
Convention or series no.
Author(s) de Cock J., Heederik D., Hoek F., Boleij J., Kromhout H.
Title Urinary excretion of tetrahydropht[h]alimide in fruit growers with dermal exposure to captan
Bibliographic information Aug. 1995, Vol.28, No.2, p.245-256. Illus. 29 ref.
Abstract Uptake of captan by pesticide applicators was measured by urinary monitoring of its metabolite, tetrahydrophthalimide (THPI). Respiratory and dermal exposures were estimated by personal air sampling and skin patches. Dermal exposure showed a clear relation to THPI in urine when exposure was estimated from skin pads on the ankles and neck. No relation was found for total dermal exposure or for respiratory exposure. Protection of the skin by using a cabin on the tractor and wearing rubber boots resulted in a lower uptake of captan. Results indicate that the skin is the major route of absorption and that there is an apparent contribution of specific body areas.
Descriptors (primary) captan; tetrahydrophthalimide; pesticides; skin absorption; biological and medical tests; exposure evaluation; urinary metabolites; orchards; crop protection
Descriptors (secondary) protective clothing; determination in urine; air sampling; Netherlands
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Exposure evaluation
Amides
Agriculture
Agricultural chemicals