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CISDOC database
| Document ID (ISN) | 66389 |
| CIS number |
96-1086 |
| ISSN - Serial title |
0140-6736 - Lancet |
| Year |
1996 |
| Convention or series no. |
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| Author(s) |
Gilks C.F., Ojoo S.A., Ojoo J.C., Brindle R.J., Paul J., Batchelor B.I.F., Kimari J.N., Newnham R., Bwayo J., Plummer F.A., Warrell D.A. |
| Title |
Invasive pneumococcal disease in a cohort of predominantly HIV-1 infected female sex-workers in Nairobi, Kenya |
| Bibliographic information |
16 Mar. 1996, Vol.347, No.9003, p.718-723. Illus. 31 ref. |
| Abstract |
Follow-up (1989-1992) cohort study of 719 female prostitutes in sub-Saharan Africa, 132 (18.4%) of whom remained HIV negative at the end of the follow-up period. Invasive pneumococcal disease (pneumonia, maxillary sinusitis, fever etc.) was diagnosed in 79 of the women who were seropositive at the end of the follow-up period, as opposed to only one among those who remained seronegative (RR 17.8, 95% CI 2.5-126.5; incidence rate 42.5/1000 person-yrs in seropositive women). It appears that the bacterium Strep pneumoniae causes more disease, at an earlier stage of HIV immunosuppression, than other bacteria such as Mycobacterium tuberculosis. |
| Descriptors (primary) |
Africa; bacterial diseases; sex workers; pneumonia; immunodeficiency syndrome; infectious diseases |
| Descriptors (secondary) |
cohort study; Kenya |
| Document type |
D - Periodical articles |
| Country / State or Province | Canada; United Kingdom; Kenya |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
Biological hazards
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| Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar)
Bacterial and parasitic diseases
HIV/AIDS
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