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Document ID (ISN)66389
CIS number 96-1086
ISSN - Serial title 0140-6736 - Lancet
Year 1996
Convention or series no.
Author(s) Gilks C.F., Ojoo S.A., Ojoo J.C., Brindle R.J., Paul J., Batchelor B.I.F., Kimari J.N., Newnham R., Bwayo J., Plummer F.A., Warrell D.A.
Title Invasive pneumococcal disease in a cohort of predominantly HIV-1 infected female sex-workers in Nairobi, Kenya
Bibliographic information 16 Mar. 1996, Vol.347, No.9003, p.718-723. Illus. 31 ref.
Abstract Follow-up (1989-1992) cohort study of 719 female prostitutes in sub-Saharan Africa, 132 (18.4%) of whom remained HIV negative at the end of the follow-up period. Invasive pneumococcal disease (pneumonia, maxillary sinusitis, fever etc.) was diagnosed in 79 of the women who were seropositive at the end of the follow-up period, as opposed to only one among those who remained seronegative (RR 17.8, 95% CI 2.5-126.5; incidence rate 42.5/1000 person-yrs in seropositive women). It appears that the bacterium Strep pneumoniae causes more disease, at an earlier stage of HIV immunosuppression, than other bacteria such as Mycobacterium tuberculosis.
Descriptors (primary) Africa; bacterial diseases; sex workers; pneumonia; immunodeficiency syndrome; infectious diseases
Descriptors (secondary) cohort study; Kenya
Document type D - Periodical articles
Country / State or ProvinceCanada; United Kingdom; Kenya
Subject(s) Occupational pathology
Broad subject area(s) Biological hazards
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Bacterial and parasitic diseases