| Document ID (ISN) | 66379 |
| CIS number |
96-773 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
1995 |
| Convention or series no. |
|
| Author(s) |
Potashnik G., Porath A. |
| Title |
Dibromochloropropane (DBCP): A 17-year reassessment of testicular function and reproductive performance |
| Bibliographic information |
Nov. 1995, Vol.37, No.11, p.1287-1292. 18 ref. |
| Abstract |
15 men with DBCP-induced testicular dysfunction, and whose last contact with DBCP (nemagon) was 17 to 22 years ago, were periodically evaluated since initial diagnosis in 1977. Sperm count recovery was evident within 36 to 45 months of the last exposure in 3 of the 9 azoospermic and in 3 of the 6 oligozoospermic men with no improvement thereafter. An increase in plasma follicle-stimulating hormone and luteinizing hormone and a decrease in testosterone level were detected in the severely affected individuals. There was no increase in the rate of spontaneous abortions and congenital malformations among pregnancies conceived during or after exposure. |
| Descriptors (primary) |
agricultural chemicals; spermatogenic disturbances; Nemagon; antifertility effects |
| Descriptors (secondary) |
length of exposure; long-term study |
| Document type |
D - Periodical articles |
| Country / State or Province | Israel |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agricultural chemicals
Halogenated hydrocarbons
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Diseases of the reproductive system
|
