ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)66126
CIS number 96-259
ISSN - Serial title 0886-022X - Renal Failure
Year 1995
Convention or series no.
Author(s) Savolainen H.
Title Cadmium-associated renal disease
Bibliographic information 1995, Vol.17, no.5, p.483-487. 30 ref.
Abstract The metabolism, toxicity and renal effects of cadmium are reviewed. The long half-life of cadmium in the human organism causes its accumulation in the liver and kidneys. Renal effects include early tubular dysfunction manifested by proteinuria, amino aciduria, glucosuria, phosphaturia and calcium wastage. Chronic effects include decrease in the glomerular filtration rate and increased rate of kidney stone disease. Biological monitoring of cadmium absorption includes determination of urinary cadmium and of low molecular weight marker proteins.
Descriptors (primary) toxicology; cadmium; renal diseases
Descriptors (secondary) metabolic process; renal dysfunction; proteinuria; urinary lithiasis; urinary excretion
Document type D - Periodical articles
Country / State or ProvinceSwitzerland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the kidney and the urinary system
Cadmium and compounds
Inorganic substances