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Document ID (ISN)64875
CIS number 95-1408
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1994
Convention or series no.
Author(s) White R.F., Robins T.G., Proctor S., Echeverria D., Rocskay A.S.
Title Neuropsychological effects of exposure to naphtha among automotive workers
Bibliographic information Feb. 1994, Vol.51, No.2, p.102-112. 70 ref.
Abstract The association between exposure to naphtha and neurobehavioural measures was examined prospectively over one year among workers employed at an automotive plant that used naphtha to calibrate fuel injectors. In June 1988, 248 workers were tested and 185 of these were tested again in 1989. Concentrations of naphtha at the plant ranged from 6 to 709mg/m3, although exposure was greater in 1988 than in 1989. Duration of exposure for individual subjects ranged from 0.8-7.3yrs. Threshold model analyses of the 1989 data showed an association between score on visual reproductions immediate recall and daily exposure to naphtha at or above 1,050h x mg/m3. Models of chronic exposure showed no associations between chronic exposure and negative neurobehavioural outcome. Results suggest that naphtha produces mild acute reversible effects on function of the central nervous system at or above daily exposure of 540h x mg/m3 (approximately 90ppm/h).
Descriptors (primary) solvent naphtha; organic solvents; chronic poisoning; motor vehicle industry; neuropsychic effects
Descriptors (secondary) conditions of exposure; nervous function tests; chronic forms; comparative study; cohort study; behaviour study; experimental determination; naphtha
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Motor vehicle manufacturing industry
Diseases of the nervous system