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Document ID (ISN)64863
CIS number 95-1422
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1994
Convention or series no.
Author(s) Lin S., Marshall E.G., Davidson G.K.
Title Potential parental exposure to pesticides and limb reduction defects
Bibliographic information June 1994, Vol.20, No.3, p.166-179. 40 ref.
Abstract The effects of the potential pesticide exposure of parents on the risk of limb reduction defects in their offspring was studied in a case-control study utilizing New York State Congenital Malformation Register data. Persons with limb reduction defects and controls were compared in terms of parental occupations and counties of residence. Parental occupations and industries reported on birth certificates were qualitatively rated by industrial hygienists to estimate potential pesticide exposures. Residential exposures were estimated from agricultural census data according to county of residence. Neither parental exposure to pesticides nor farming occupation had an effect on the risk of total limb reduction defects. Those persons with limb reduction defects who had additional defects showed weak but consistent elevated risks in relation to parental occupational pesticide exposure. Cases of limb reduction defect with additional malformations appear to be associated with parental occupational pesticide exposure. In appendix: detailed data on potential pesticide exposure based on hygienists' assessments.
Descriptors (primary) children; pesticides; agriculture; teratogenic effects; genetic effects
Descriptors (secondary) USA; statistical evaluation; case-control study; occupation disease relation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Agricultural chemicals
Genetic factors in reaction to exposures