|Document ID (ISN)||64863|
|ISSN - Serial title
||0355-3140 - Scandinavian Journal of Work, Environment and Health
|Convention or series no.
||Lin S., Marshall E.G., Davidson G.K.
||Potential parental exposure to pesticides and limb reduction defects
||June 1994, Vol.20, No.3, p.166-179. 40 ref.
||The effects of the potential pesticide exposure of parents on the risk of limb reduction defects in their offspring was studied in a case-control study utilizing New York State Congenital Malformation Register data. Persons with limb reduction defects and controls were compared in terms of parental occupations and counties of residence. Parental occupations and industries reported on birth certificates were qualitatively rated by industrial hygienists to estimate potential pesticide exposures. Residential exposures were estimated from agricultural census data according to county of residence. Neither parental exposure to pesticides nor farming occupation had an effect on the risk of total limb reduction defects. Those persons with limb reduction defects who had additional defects showed weak but consistent elevated risks in relation to parental occupational pesticide exposure. Cases of limb reduction defect with additional malformations appear to be associated with parental occupational pesticide exposure. In appendix: detailed data on potential pesticide exposure based on hygienists' assessments.
||children; pesticides; agriculture; teratogenic effects; genetic effects
||USA; statistical evaluation; case-control study; occupation disease relation
||D - Periodical articles
|Country / State or Province||USA|
||Agriculture, fishing, animal husbandry
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures