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Document ID (ISN)64556
CIS number 95-1008
ISSN - Serial title 1250-3274 - Archives des maladies professionnelles et de médecine du travail
Year 1994
Convention or series no.
Author(s) Houeto P., Chabaux C., Levillain P., Fournier P.E.
Title Cutaneous reactions due to pyridinecarboxaldehyde, thiophenecarboxaldehyde - Isomerism
Original title Réactions cutanées aux pyridinecarbaldéhydes et thiophènecarbaldéhydes - Notion d'isomérie [in French]
Bibliographic information 1994, Vol.55, No.6, p.467-469. Illus. 16 ref.
Abstract A 27-year-old woman who underwent skin exposure to pyridinecarboxaldehyde and thiophenecarboxaldehyde at the workplace. In patch tests, 3-pyridinecarboxaldehyde produced urticaria whereas 2-pyridinecarboxaldehyde isomer induced eczema and no reaction was observed with 4-pyridinecarboxaldehyde. Patch tests made with thiophenecarboxaldehyde showed that the patient was sensitive to 3-thiophenecarboxaldehyde, which induced irritant erythema whereas there was no reaction with its isomer 2-thiophenecarboxaldehyde. Thus, depending on the position of the carbonyl carbon on the pyridine (ortho, meta or para) or thiophene ring, different reactions can occur.
Descriptors (primary) aldehydes; thiophenecarboxaldehydes; skin diseases; occupational pathology; pyridinecarboxaldehydes
Descriptors (secondary) chemical industry; case study; 3-thiophenecarboxaldehyde; 2-thiophenecarboxaldehyde; 3-pyridinecarboxaldehyde; 4-pyridinecarboxaldehyde; skin tests; 2-pyridinecarboxaldehyde
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Heterocyclic compounds