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CISDOC database

Document ID (ISN)64059
CIS number 95-579
ISSN - Serial title 0095-6562 - Aviation, Space, and Environmental Medicine
Year 1994
Convention or series no.
Author(s) Stein T.P., Schluter M.D., Boden G.
Title Development of insulin resistance by astronauts during spaceflight
Bibliographic information Dec. 1994, Vol.65, No.12, p.1091-1096. Illus. 25 ref.
Abstract Dietary intake and urine output were monitored continuously for four crewmembers of a Space Shuttle mission from 11 days before launch to 7 days after landing (total 27 days). The urinary C-peptide excretion rate was used as a marker for insulin secretion. Mean inflight C-peptide excretion rates were significantly lower than either the pre- or postflight rates. The progressively increasing C-peptide excretion during 9 days of spaceflight is indicative of the development of insulin resistance in astronauts.
Descriptors (primary) proteins; space travel; metabolic disturbances; insulin
Descriptors (secondary) determination in urine; peptides
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Transport and communications
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Space travel
Endocrine diseases