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Document ID (ISN)63994
CIS number 95-577
ISSN - Serial title 1250-3274 - Archives des maladies professionnelles et de médecine du travail
Year 1994
Convention or series no.
Author(s) Houeto P., Abiola F.A., Diatta F.
Title Cholinesterase activity of Senegalese applicators exposed to organophosphates (fenitrothion)
Original title Exposition au fénitrothion et activité cholinestérasique chez des applicateurs de pesticides au Sénégal [in French]
Bibliographic information 1994, Vol.55, No.2, p.119-123. 7 ref.
Abstract Among the pesticides currently used in agriculture, organophosphates occupy a dominant position. They have a specific action in inhibiting enzymes, namely cholinesterases. Given the number of cases of human poisoning in agriculture, it is important to measure levels of cholinesterases to evaluate the risks. Cholinesterase activity was measured with Ellman's colorimetric method in whole blood, erythrocytes and plasma of workers exposed to Sumithion (fenitrothion 500g/L U.L.V. and C.E.) in Senegal, which is one of the most commonly used organophosphate insecticides in that country, and as a function of the spraying equipment used and of the type of application. Prevention of cases of poisoning calls for medical, technical and hygienic measures, and, above all, for the health education of workers. A systematic determination of globular and plasma cholinesterases is recommended at the time of the initial medical examination of workers, the results of which can then be used for comparison purposes during later tests.
Descriptors (primary) cholinesterase monitoring; Senegal; metathion; pesticides; exposure evaluation; organophosphorus compounds
Descriptors (secondary) exposure tests; developing countries; description of technique
Document type D - Periodical articles
Country / State or ProvinceSenegal
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Biological monitoring
Esters and salts
Agricultural chemicals
Exposure evaluation