ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)63969
CIS number 95-632
ISSN - Serial title 0007-5914 - Bundesgesundheitsblatt
Year 1994
Convention or series no.
Author(s) Appel K.E.
Title On the carcinogenicity of pentachlorophenol
Original title Zur kanzerogenen Wirkung von Pentachlorphenol [in German]
Bibliographic information Aug. 1994, Vol.37, No.8, p.334-341. 61 ref.
Abstract Pentachlorophenol (PCP) has been widely used in industry, agriculture, and in homes as a pesticide and herbicide. It finds its widest use in wood impregnation. Data on the carcinogenicity of PCP are reviewed. The substance is carcinogenic in B6C3F1-mice. In addition, there is evidence that some metabolites of PCP are genotoxic. Epidemiologic studies have not provided proof or disproof of a carcinogenic effect in humans. The present exposure limit of 1µg/m3 air recommended by the German Bureau of Health is on the safe side on the basis of present knowledge.
Descriptors (primary) carcinogens; carcinogenic effects; hazard evaluation; pentachlorophenol
Descriptors (secondary) herbicides; literature survey; dangerous substances; Germany; pesticides; agriculture; permissible levels; epidemiologic study; animal experiments; genetic effects; wood impregnation
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Phenols and phenolic compounds
Genetic factors in reaction to exposures