| Document ID (ISN) | 63742 |
| CIS number |
95-264 |
| Year |
1994 |
| Convention or series no. |
ECETOC Technical Report No.57
|
| Title |
Polypropylene production and colorectal cancer |
| Bibliographic information |
European Centre for Ecotoxicology and Toxicology of Chemicals, 4 Ave. E. Van Nieuwen huyse, 1160 Bruxelles, Belgium, Feb. 1994. 40p. 108 ref. |
| Abstract |
Polypropylene has been produced for over 35 years. It has many uses, including food packaging. Implantation of polypropylene produced sarcomas in experimental animals, apparently due to tissue trauma. The monomer, propylene, was not carcinogenic in a two-year inhalation study with mice and rats. Two early epidemiologic studies of polypropylene production workers and polypropylene carpet manufacturing workers showed an excess of colorectal cancer, but subsequent studies on these populations did not reproduce the observation, and studies on polypropylene production workers in several countries were also negative. Thus, specific medical surveillance programmes among these workers are not warranted. |
| Descriptors (primary) |
propylene; plastics industry; gastrointestinal cancer; polypropylene |
| Descriptors (secondary) |
epidemiologic study |
| Document type |
E - Books, reports, proceedings |
| Country / State or Province | Belgium |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Chemical industry
Gastrointestinal diseases
Aliphatic and alicyclic hydrocarbons
Plastics industry
|
