|Document ID (ISN)||63412|
|Convention or series no.
||BUA Report 58
Gesellschaft Deutscher Chemiker (GDCh) - Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
||Butylated hydroxytoluene (2,6-bis(1,1-dimethylethyl)-4-methylphenol)
||S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1994. xv, 116p. 197 ref.
||Only a few studies are available on the sensitizing effects of butylated hydroxytoluene (2,6-di-tert-butyl-p-cresol) in humans. In one study it is described as mildly irritating to the skin and moderately sensitizing in human patch tests; contact dermatitis and allergic reactions have also been reported. Animal studies indicate that the substance affects the lungs, liver, kidneys and thyroid gland; contradictory results are available on carcinogenicity, mutagenicity and reproduction disturbances.
||2,6-di-tert-butyl-p-cresol; ecotoxicology; toxicology; Germany
||toxic effects; literature survey; irritants; eczema; allergic reactivity; animal experiments; comment on law; comment on directive; criteria document; sensitizers
||E - Books, reports, proceedings
|Country / State or Province||Germany|
||Toxic and dangerous substances
|Broad subject area(s)