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CISDOC database

Document ID (ISN)63412
CIS number 94-2027
ISBN(s) 3-7776-0574-3
Year 1994
Convention or series no. BUA Report 58
Gesellschaft Deutscher Chemiker (GDCh) - Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Title Butylated hydroxytoluene (2,6-bis(1,1-dimethylethyl)-4-methylphenol)
Bibliographic information S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1994. xv, 116p. 197 ref.
Abstract Only a few studies are available on the sensitizing effects of butylated hydroxytoluene (2,6-di-tert-butyl-p-cresol) in humans. In one study it is described as mildly irritating to the skin and moderately sensitizing in human patch tests; contact dermatitis and allergic reactions have also been reported. Animal studies indicate that the substance affects the lungs, liver, kidneys and thyroid gland; contradictory results are available on carcinogenicity, mutagenicity and reproduction disturbances.
Descriptors (primary) 2,6-di-tert-butyl-p-cresol; ecotoxicology; toxicology; Germany
Descriptors (secondary) toxic effects; literature survey; irritants; eczema; allergic reactivity; animal experiments; comment on law; comment on directive; criteria document; sensitizers
Document type E - Books, reports, proceedings
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Alcohols
Pollution control