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CISDOC database

Document ID (ISN)63387
CIS number 94-1954
ISSN - Serial title 0095-6562 - Aviation, Space, and Environmental Medicine
Year 1994
Convention or series no.
Author(s) Gmünder F.K., Konstantinova I., Cogoli A., Lesnyak A., Bogomolov W., Grachov A.W.
Title Cellular immunity in cosmonauts during long duration spaceflight on board the orbital MIR station
Bibliographic information May 1994, Vol.65, No.5, p.419-423. 26 ref.
Abstract Delayed-type hypersensitivity (DTH) was tested in five cosmonauts by intradermal application of seven antigens and a control. In four of the five cosmonauts, reaction scores of DTH-responses below the warning level were noted either during the flight or following landing. Results confirm earlier observations of a decreased lymphocyte function following spaceflights and support the theory of a possibly impaired cell-mediated immunity under stress in association with spaceflight.
Descriptors (primary) space travel; immunobiological changes
Descriptors (secondary) lymphocytes; allergy tests; antigens
Document type D - Periodical articles
Country / State or ProvinceSwitzerland; Russian Federation
Subject(s) Occupational physiology
Broad subject area(s) Industries and occupations
Browse category(ies) Space travel