Document ID (ISN) | 63362 |
CIS number |
94-1989 |
ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
Year |
1994 |
Convention or series no. |
|
Author(s) |
Crump K.S. |
Title |
Risk of benzene-induced leukemia: A sensitivity analysis of the Pliofilm cohort with additional follow-up and new exposure estimates |
Bibliographic information |
June 1994, Vol.42, No.2, p.219-242. 34 ref. |
Abstract |
This reports updates an earlier risk assessment for benzene-induced leukaemia which was used by OSHA in the establishment of permissible exposure limits. The present study was based on mortality data on a cohort of workers employed at two Pliofilm manufacturing plants where there were relatively high exposures to benzene. New risk estimates are derived using follow-up data to 1987 and using new exposure estimates. Results indicate a significant excess of acute myelocytic or acute monocytic leukaemia and a strong dose-response trend. |
Descriptors (primary) |
leukaemia; hazard evaluation; benzene |
Descriptors (secondary) |
mortality; mathematical models; cohort study; exposure evaluation |
Document type |
D - Periodical articles |
Country / State or Province | USA |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Aromatic hydrocarbons Risk evaluation Leukaemia
|