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CISDOC database

Document ID (ISN)63247
CIS number 94-2008
Year 1994
Convention or series no. ECETOC JACC No.24
Title Pentafluoroethane (HFC 125)
Bibliographic information European Centre for Ecotoxicology and Toxicology of Chemicals, Ave. E. Van Nieuwenhuyse 4, Bte. 6, 1160 Bruxelles, Belgium, May 1994. i, 25p. 30 ref.
Abstract Pentafluoroethane is a non-flammable colourless gas that is currently under development as an alternative to chlorofluorocarbons and is not yet available commercially. Its toxicity is very low (the 4h LC50 in rats is greater than 3,928,000 mg/m3 = 800,000ppm). Cardiac sensitization in dogs is observed above 100,000ppm. No mutagenicity or developmental toxicity has been seen in laboratory experiments. No effects on human beings have been reported. An occupational exposure limit (8h time-weighted average) of 1000ppm is recommended by producers.
Descriptors (primary) threshold limit values; toxicology; pentafluoroethane; chemical industry
Descriptors (secondary) criteria document; literature survey
Document type E - Books, reports, proceedings
Country / State or ProvinceBelgium
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Chemical industry
Occupational exposure limits
Halogenated hydrocarbons