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Document ID (ISN)63223
CIS number 94-1998
ISSN - Serial title 0002-9262 - American Journal of Epidemiology
Year 1993
Convention or series no.
Author(s) Kristensen P., Irgens L.M., Daltveit A.K., Andersen A.
Title Perinatal outcome among children of men exposed to lead and organic solvents in the printing industry
Bibliographic information 15 Jan. 1993, Vol.137, No.2, p.134-144. 50 ref.
Abstract The study investigated the relation between paternal occupational exposures to lead and solvents and postconception events. Records of 6,251 infants born between 1967-1986 were used in the study. The adjusted odds ratio for early preterm birth (16-27 weeks) was 5.4 (95% confidence interval (CI) 1.7-17.4) for infants with paternal exposure to solvents and 8.6 (95% CI 2.7-27.3) for children whose fathers were in the lead plus solvents category. The adjusted odds ratio for all perinatal deaths was 2.4 (95% CI 1.2-4.9) for children with fathers in the lead-exposed group and 1.9 (95% CI 0.96-3.7) for children with fathers in the lead plus solvents group. An increased risk of cleft lip was demonstrated, with interaction between sex and paternal lead exposure: the standardized morbidity ratio for boys in the two subgroups with lead exposure was 4.1 (95% CI 1.8-8.1). Paternal exposure had little impact on birth weight, intra-uterine growth, or total number of birth defects.
Descriptors (primary) embryotoxic effects; printing industry; organic solvents; parental exposure; lead; children
Descriptors (secondary) Norway; cohort study; solvents
Document type D - Periodical articles
Country / State or ProvinceNorway
Subject(s) Paper-making and printing
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Printing, photography and photocopying industry
Lead and compounds