|Document ID (ISN)||63223|
|ISSN - Serial title
||0002-9262 - American Journal of Epidemiology
|Convention or series no.
||Kristensen P., Irgens L.M., Daltveit A.K., Andersen A.
||Perinatal outcome among children of men exposed to lead and organic solvents in the printing industry
||15 Jan. 1993, Vol.137, No.2, p.134-144. 50 ref.
||The study investigated the relation between paternal occupational exposures to lead and solvents and postconception events. Records of 6,251 infants born between 1967-1986 were used in the study. The adjusted odds ratio for early preterm birth (16-27 weeks) was 5.4 (95% confidence interval (CI) 1.7-17.4) for infants with paternal exposure to solvents and 8.6 (95% CI 2.7-27.3) for children whose fathers were in the lead plus solvents category. The adjusted odds ratio for all perinatal deaths was 2.4 (95% CI 1.2-4.9) for children with fathers in the lead-exposed group and 1.9 (95% CI 0.96-3.7) for children with fathers in the lead plus solvents group. An increased risk of cleft lip was demonstrated, with interaction between sex and paternal lead exposure: the standardized morbidity ratio for boys in the two subgroups with lead exposure was 4.1 (95% CI 1.8-8.1). Paternal exposure had little impact on birth weight, intra-uterine growth, or total number of birth defects.
||embryotoxic effects; printing industry; organic solvents; parental exposure; lead; children
||Norway; cohort study; solvents
||D - Periodical articles
|Country / State or Province||Norway|
||Paper-making and printing
|Broad subject area(s)
Printing, photography and photocopying industry
Lead and compounds