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CISDOC database

Document ID (ISN)62453
CIS number 94-1021
ISBN(s) 92-826-5582-2
Year 1993
Convention or series no. EUR 14991 EN
Author(s) Sullivan F.M., Watkins W.J., van der Venne M.T.
Commission of the European Communities
Title The toxicology of chemicals - 2. Reproductive toxicity: Volume 1 - Summary reviews of the scientific evidence
Bibliographic information Office for Official Publications of the European Communities, 2985 Luxembourg, Grand Duchy of Luxembourg, 1993. ix, 431p. Bibl.ref. Price: ECU 40.00.
Abstract This volume contains reviews of 26 chemicals of industrial interest, about half of which are solvents to which there is wide exposure, three major drugs of addiction (heroin, cocaine, morphine) and methadone. Also included are CEC guidelines for the Evaluation of Reproductive Toxicity. Each monograph provides a general introduction to the chemistry and uses of the chemical followed by a brief review of general toxicity, kinetics and metabolism and detailed reviews of animal and human data on reproductive effects (endocrine and gonadal effects, fertility and pregnancy studies).
Descriptors (primary) antifertility effects; European Communities; solvents; harmful substances; toxicology
Descriptors (secondary) toxic effects; hexachlorophene; epidemiological aspects; dichloromethane; chloroform; carbon tetrachloride; 1,2-dichloroethane; 1,1,1-trichloroethane; 1,1,2,2-tetrachloroethane; acetone; acetaldehyde; trichloroethylene; tetrachloroethylene; chlorobutadiene; propylene dichloride; toluene; heroin; morphine; bis(ethylhexyl) phthalate; dioctyl phthalate; cocaine; isopropyl alcohol; 2,4-tolylene diisocyanate; methadone hydrochloride; p-xylene; isopropyl acetate; dimethyl phthalate; diethyl phthalate; dibutyl phthalate; diisobutyl phthalate; Nemagon; complications of pregnancy; xylene; m-xylene; o-xylene; list of chemical substances; animal experiments; gonadotropic effects; endocrine effects; selenium; criteria document; literature survey
Document type E - Books, reports, proceedings
Country / State or ProvinceEuropean Union
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Toxicology