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CISDOC database

Document ID (ISN)62410
CIS number 94-1017
ISBN(s) 3-7776-0555-7
Year 1993
Convention or series no. BUA Report 90
Author(s)
Gesellschaft Deutscher Chemiker (GDCh) Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Title Epichlorohydrin (1-chloro-2,3-epoxypropane)
Bibliographic information S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1993. xviii, 132p. Bibl.ref. Price: DEM 88.00.
Abstract The sensitizing properties of epichlorohydrin have been demonstrated in animal experiments as well as in cases of occupational contact dermatitis. Direct contact of the substance with the skin or mucous membranes can cause strong irritation or burns. An epidemiological study of exposed workers revealed an increased incidence of skin diseases. Animal studies have shown epichlorohydrin to be carcinogenic; no firm conclusions on human carcinogenicity can be drawn from available epidemiological studies.
Descriptors (primary) Germany; ecotoxicology; epichlorohydrin; toxicology
Descriptors (secondary) toxic effects; literature survey; irritants; carcinogens; skin absorption; caustic substances; criteria document; eczema; sensitizers; animal experiments; environmental pollution; legislation; skin diseases
Document type E - Books, reports, proceedings
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Ethylene oxide
Pollution control
Ethers