Document ID (ISN) | 62313 |
CIS number |
94-880 |
ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
Year |
1993 |
Convention or series no. |
|
Author(s) |
Frumkin H., Gerr F. |
Title |
Dimercaptosuccinic acid in the treatment of depression following lead exposure |
Bibliographic information |
Dec. 1993, Vol.24, No.6, p.701-706. 17 ref. |
Abstract |
Long-term exposure to lead is known to cause a variety of neurotoxic manifestations, including symptoms of depression. Dimercaptosuccinic acid (DMSA), a recently approved oral chelating agent, can diminish the body burden of lead, but few cases of documented clinical improvement following treatment have been reported. We report a case of moderate to severe depression in a long-term lead worker that appeared to respond dramatically to DMSA. This response suggests a possible therapeutic role for DMSA in the treatment of depression in lead-exposed patients. |
Descriptors (primary) |
lead; dimercaptosuccinic acid; chelation therapy; chronic poisoning; toxic substances |
Descriptors (secondary) |
case study |
Document type |
D - Periodical articles |
Country / State or Province | USA |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Occupational medicine, epidemiology
|
Browse category(ies) |
Lead and compounds Inorganic substances
|