| Document ID (ISN) | 62271 |
| CIS number |
94-953 |
| ISSN - Serial title |
0096-1736 - Journal of Occupational Medicine |
| Year |
1993 |
| Convention or series no. |
|
| Author(s) |
Heseltine E., Peltonen K., Sorsa M., Vainio H. |
| Title |
Assessment of the health hazards of 1,3-butadiene and styrene |
| Bibliographic information |
Nov. 1993, Vol.35, No.11, p.1089-1095. 6 ref. |
| Abstract |
Report on a meeting held in Espoo, Finland, 18-21 April 1993, on the health hazards of 1,3-butadiene and styrene. The main topics were occurrence and exposure, dose measurement, protein and DNA adducts as markers of exposure, reproductive effects and neurotoxicity, genetic toxicity, cancer. The two substances have carcinogenic effects in laboratory studies but wide differences between species make extrapolation to humans difficult. Epidemiological evidence associating butadiene exposure with cancer is strong, but the data on styrene are still equivocal. Research in several areas is needed. |
| Descriptors (primary) |
carcinogens; styrene; chemical hazards; hazard evaluation; butadiene |
| Descriptors (secondary) |
neurotoxic effects; antifertility effects; round-up; conference; cancer |
| Document type |
D - Periodical articles |
| Country / State or Province | Finland; France |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Risk evaluation
Genetic factors in reaction to exposures
Aromatic hydrocarbons
Aliphatic and alicyclic hydrocarbons
Butadiene
|
