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Document ID (ISN)62258
CIS number 94-974
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1993
Convention or series no.
Author(s) Brouwer R., van Maarleveld K., Ravensberg L., Meuling W., de Kort W., van Hemmen J.J.
Title Skin contamination, airborne concentrations, and urinary metabolite excretion of propoxur during harvesting of flowers in greenhouses
Bibliographic information Nov. 1993, Vol.24, No.5, p.593-603. Illus. 29 ref.
Abstract In eight greenhouses used for carnation culture, workers engaged in harvesting (n=16) were monitored for dermal and respiratory exposure and urinary excretion of propoxur. Total estimated dermal and respiratory exposure during harvesting ranged from 0.2 to 46mg and from 3 to 278µg, respectively. To study the relationship between external and internal exposure to propoxur, respiratory and dermal exposure levels were compared with the total amount of 2-isopropoxyphenol (IPP), the major metabolite of propoxur, excreted in urine in 24hrs. The Pearson correlation coefficient between dermal exposure and the total amount of excreted IPP was 0.95. A correlation coefficient of 0.84 was found between respiratory exposure and the amount of IPP excreted. The latter association was probably caused by the covariation of respiratory and dermal exposure levels (r=0.85). Calculations indicated that dermal exposure could account for >80% of the amount of excreted IPP. On the basis of the amount of IPP excreted, there was no reason to suspect increased health risks for workers from exposure to propoxur during harvesting.
Descriptors (primary) arprocarb; pesticides; harvesting; determination in urine; flower and perfume-plant growing; exposure tests; dermatological effects
Descriptors (secondary) sampling and analysis; agricultural operations
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Biological monitoring
Amides
Agriculture
Agricultural chemicals