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CISDOC database

Document ID (ISN)62246
CIS number 94-1072
ISSN - Serial title 0098-7484 - Journal of the American Medical Association
Year 1993
Convention or series no.
Author(s) Wood R.C., MacDonald K.L., White K.E., Hedberg C.W., Hanson M., Osterholm M.T.
Title Risk factors for lack of detectable antibody following hepatitis B vaccination of Minnesota health care workers
Bibliographic information 22-29 Dec. 1993, Vol.270, No.24, p.2935-2939. Illus. 39 ref.
Abstract A total of 595 health care workers who had received hepatitis B vaccine underwent postvaccination testing for hepatitis B antibodies within 6 months of receiving the third dose of vaccine. Five variables were independently associated with a lack of antibodies: vaccine brand, smoking status, sex, age and body mass index. Results indicate that certain populations of health care workers are at increased risk of not responding to hepatitis B vaccination. Further studies evaluating the immunogenicity of currently available hepatitis B vaccines in persons at high risk for primary vaccine failure are needed.
Descriptors (primary) USA; vaccination; health care personnel; infectious hepatitis
Descriptors (secondary) smoking; antibodies; body weight; age-linked differences; sex-linked differences; survey
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Biological hazards
Browse category(ies) Liver diseases
Health care services
Bacterial and parasitic diseases
Viral diseases (other than aids)