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Document ID (ISN)62083
CIS number 94-555
ISSN - Serial title 0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku
Year 1993
Convention or series no.
Author(s) Kishi R., Katakura Y., Yuasa J., Miyake H.
Title Association of parents' occupational exposure with cancer in children. A case-control study of acute lymphoblastic leukaemia
Original title Shōni akusei shuyō to ryōshin no jūji suru sangyō oyobi shokugyō no kanren. Kyūsei rinpagakyūsei hakketsubyō no shōrei taishō kenkyū [in Japanese]
Bibliographic information Nov. 1993, Vol.35, No.6, p.515-529. 43 ref.
Abstract Cases of acute lymphoblastic leukaemia in children less than 15 years of age identified between 1980 and 1990 in four hospitals in northern Japan (147 cases) were matched by age and sex with other hospital patients and by place of residence and sex with children in the general population. Data on occupation and exposure to various agents were obtained from mothers by interview and from fathers by mail questionnaire. More fathers of the cases were engaged in agriculture, medicine or science than were fathers of controls; more mothers were engaged in agriculture. In comparison with hospital controls, paternal preconceptual exposure to chemicals and prenatal exposure to pesticides and maternal prenatal exposure to benzine and spray pesticides were important risk factors. In comparison with population controls, maternal prenatal exposure to benzine and exposure to spray paints before the appearance of leukaemia were highly significant risks.
Descriptors (primary) children; Japan; parental exposure; acute leukaemia; pesticides; organic solvents; occupation disease relation
Descriptors (secondary) petroleum hydrocarbons; epidemiologic study; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Leukaemia
Agricultural chemicals