ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)61786
CIS number 94-303
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 1993
Convention or series no.
Author(s) Buratti M., Pellegrino O., Valla C., Colombi A.
Title Biological monitoring of occupational exposure to inhalation anaesthetics - Determination of urinary nitrous oxide, halothane and isoflurane
Original title Monitoraggio biologico dell'esposizione professionale a gas e vapori anestetici - Determinazione di protossido d'azoto, alotano e isofluorano nell'urina [in Italian]
Bibliographic information Jan.-Feb. 1993, Vol.84, No.1, p.66-73. Illus. 9 ref.
Abstract A gas-chromatographic method is described for measuring the urinary concentrations of nitrous oxide, halothane and isoflurane. The detection limit (ranging from 0.03µg/L for halothane to 1µg/L for nitrous oxide), between-day precision (CV<6%) and working linear range (up to 100µg/L for halothane and 2000µg/L for nitrous oxide) were determined. A two-year experience in biological monitoring of occupationally exposed surgical staff with the proposed method is reported and confounding factors are discussed. The method is easy to perform, free from interferences and suitable for use in routine analysis in toxicological laboratories.
Descriptors (primary) halothane; inhalation anaesthetics; determination in urine; isoflurane; exposure tests; nitrous oxide
Descriptors (secondary) description of technique; operating theatres
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Biological monitoring
Halogenated hydrocarbons
Ethers
Inorganic substances