| Document ID (ISN) | 61771 |
| CIS number |
94-226 |
| ISSN - Serial title |
0173-3338 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz, Prophylaxe und Ergonomie |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Baur X., Czuppon A.B., Raulf M. |
| Title |
Case report: Extrinsic allergic alveolitis caused by an isocyanate (isocyanate alveolitis) |
| Original title |
Fallbericht: Exogen-allergische Alveolitis durch Isocyanat (Isocyanat-Alveolitis) [in German] |
| Bibliographic information |
May 1992, Vol.42, No.5, p.187-189. Illus. 5 ref. |
| Abstract |
A 54 year-old worker regularly observed episodes of fever, headache, irritation of the throat, and difficulty in breathing a few hours after exposure to an isocyanate (MDI) hardening agent. Exposure tests with MDI showed that an extrinsic allergic alveolitis developed together with restrictive ventilation, hypoxaemia, fever up to 39.2°C (axillary), and leucocytosis. In the bronchoalveolar lavage (BAL), besides agranulocytosis and eosinophilia, a strong reduction in the CD4/CD8-quotient was observed. After an interval of two years, the presence of antibodies could no longer be shown. |
| Descriptors (primary) |
diphenylmethane diisocyanate; isocyanates; extrinsic allergic alveolitis |
| Descriptors (secondary) |
case study; medical examinations; restrictive ventilatory impairment; hardeners |
| Document type |
D - Periodical articles |
| Country / State or Province | Germany |
| Subject(s) |
Metal production and metalworking
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Cyano compounds
Pneumoconioses
Isocyanates
|
