| Document ID (ISN) | 61753 |
| CIS number |
94-301 |
| ISSN - Serial title |
1775-8785 - Archives des maladies professionnelles |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Mora V., Pairon J.C., Garnier R., Laureillard J., Lionnet F., Hoguet L., Schaeffer A., Efthymiou M.L., Brochard P. |
| Title |
Acute arsine poisoning in a ferrous metal foundry: Report on two cases |
| Original title |
Intoxication aiguë par l'hydrogène arsénié dans une fonderie de métaux ferreux. A propos de deux observations [in French] |
| Bibliographic information |
1992, Vol.53, No.3, p.167-173. Illus. 21 ref. |
| Abstract |
Acute arsine poisoning was observed in 2 workers employed in a ferrous metal foundry. One presented an acute haemolysis with acute renal failure, requiring haemodialysis. Renal function slowly recovered but high blood pressure was observed secondarily. The 2nd case presented as predominantly cytolytic hepatitis on the 20th day after acute haemolysis. The evolution was rapidly resolutive, with no transfusion needed. The hypothesis of a causal role of arsine intoxication in this hepatitis is therefore possible. Subsequent atmospheric measurements in the workplace showed detectable amounts of arsine during the shovelling of the scories: results were < or equal to the threshold limit value when the operations were performed in dry conditions. In contrast, an atmospheric level of 60ppm was observed when water was added to the scories. This could be due to arsenical impurities present in ferrosilicium and calcium carbide used in the foundry. These observations underline the potential risk of arsine intoxication in such industries and raise the possibility of a delayed cytolytic hepatitis. |
| Descriptors (primary) |
acute poisoning; arsine; iron and steel industry; foundries; smelting plants |
| Descriptors (secondary) |
acute toxicity; case study; haemolysis; symptoms; ferrosilicon; determination in urine; nephrotoxic effects; sampling and analysis; urine cytology; description of technique; emergency treatment |
| Document type |
D - Periodical articles |
| Country / State or Province | France |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Arsenic and compounds
Foundries, metalcasting and forging operations
Smelting and refining operations
Iron and steel industry
|
