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CISDOC database

Document ID (ISN)61604
CIS number 94-289
ISSN - Serial title 0748-2337 - Toxicology and Industrial Health
Year 1992
Convention or series no.
Author(s) Cone J.E., Sult T.A.
Title Acquired intolerance to solvents following pesticide/solvent exposure in a building - A new group of workers at risk for multiple chemical sensitivities?
Bibliographic information July-Aug. 1992, Vol.8, No.4, p.29-39. Illus. 8 ref.
Abstract This study describes an incident involving resort hotel workers who reported various symptoms most likely associated with pesticide applications to control cockroach infestation. Many of these workers subsequently developed acquired intolerance to pesticides, solvents, or other agents, suggesting multiple chemical sensitivities (MCS). The accepted hypothesis for the outbreak is that it represents acute and chronic poisoning with a cholinesterase-inhibiting pesticide, probably the carbamate pesticide Baygon, mixed with organic solvent carriers. It is noted that in two previous building-associated pesticide poisoning cases there were far fewer MCS-like symptoms reported. It is suggested that the difference in the outbreak under review may be the ongoing nature of the exposure, namely that the repeated applications of pesticides and carriers in the same environment contrast with the evacuation and clean-up that occurred in the other two building outbreaks.
Descriptors (primary) pyrethrins; carbamates; chronic poisoning; organic solvents; pesticides
Descriptors (secondary) case study; cholinesterase; individual susceptibility; multifactor aetiology; symptoms; arprocarb
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Multiple chemical sensitivities
Amides
Agricultural chemicals