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Document ID (ISN)61389
CIS number 93-1889
ISSN - Serial title 0962-7480 - Occupational Medicine
Year 1993
Convention or series no.
Author(s) Mastrangelo G., Serena R., Marzia V.
Title Mortality from tumours in workers in an acrylic fibre factory
Bibliographic information Aug. 1993, Vol.43, No.3. p.155-158. 15 ref.
Abstract A retrospective epidemiological cohort study of mortality was undertaken in 671 workers with at least 12 months' exposure to acrylonitrile (AN) in an acrylic fibre factory at Porto Marghera, Venezia; 571 subjects had simultaneous exposure to dimethylacetamide (DMA). Observed mortality in the cohort was compared with expected mortality, calculated on the basis of the mortality rates of the general population in the Veneto region. A statistically significant excess was found in the mortality rate from intestinal and colon tumours (SMR=10.5, 4 observed). However, this finding was significant only in subgroups with 1 to 4 years exposure or 1 to 9 years latency. It is therefore concluded that there is no relationship between AN and/or DMA exposure and mortality from tumours of the colon and intestine.
Descriptors (primary) dimethylacetamide; synthetic fibres; exposure; mortality; gastrointestinal cancer; acrylonitrile
Descriptors (secondary) man-made fibres; neoplasms; epidemiologic study
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Amides
Gastrointestinal diseases
Cyano compounds