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CISDOC database

Document ID (ISN)61332
CIS number 93-1950
ISSN - Serial title 0867-8383 - Polish Journal of Occupational Medicine and Environmental Health
Year 1993
Convention or series no.
Author(s) Halkova Z., Zaykov C., Antov G., Mihaylova A., Mircheva V., Dinoeva S., Chipilska L.
Title Experimental study of subacute oral, dermal and inhalation toxicity of Bulmoscide preparation
Bibliographic information 1993, Vol.6, No.1, p.19-25. Illus. 26 ref.
Abstract The microbial product Bulmoscide is a new Bulgarian selective insecticide. The purpose of this study was to give the toxicological characteristics of subacute oral, dermal and inhalation exposure of microbial preparation Bulmoscide, which is based on bacterium Bacillus thuringiensis, serotype H-14. The study was performed on sexually mature Wistar rats of both sexes. No significant changes in non-specific, clinico-laboratory and biochemical parameters as well as morphological examinations in any tested groups compared to the control groups were revealed. The doses 110mg/kg (1.32 x 109 sp/kg) at oral administration during 90 days, 3000mg/kg (3.6 x 1010 sp/kg) in 21 day dermal application and maximum attainable concentration of dust aerosol 18mg/m3 (2.2 x 108 sp/m3) during a 30 day inhalation exposure are "no toxic effect" levels. On the basis of these data, Bulmoscide has been determined to be of low toxicity, presenting little hazard in terms of the Hygiene Classification of pesticides.
Descriptors (primary) toxic effects; bacteria; pesticides; inhalation toxicity; toxicity evaluation; dermal toxicity; biological insecticides
Descriptors (secondary) Bulgaria; animal experiments; toxic substances
Document type D - Periodical articles
Country / State or ProvinceBulgaria
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals