|Document ID (ISN)||61332|
|ISSN - Serial title
||0867-8383 - Polish Journal of Occupational Medicine and Environmental Health
|Convention or series no.
||Halkova Z., Zaykov C., Antov G., Mihaylova A., Mircheva V., Dinoeva S., Chipilska L.
||Experimental study of subacute oral, dermal and inhalation toxicity of Bulmoscide preparation
||1993, Vol.6, No.1, p.19-25. Illus. 26 ref.
||The microbial product Bulmoscide is a new Bulgarian selective insecticide. The purpose of this study was to give the toxicological characteristics of subacute oral, dermal and inhalation exposure of microbial preparation Bulmoscide, which is based on bacterium Bacillus thuringiensis, serotype H-14. The study was performed on sexually mature Wistar rats of both sexes. No significant changes in non-specific, clinico-laboratory and biochemical parameters as well as morphological examinations in any tested groups compared to the control groups were revealed. The doses 110mg/kg (1.32 x 109 sp/kg) at oral administration during 90 days, 3000mg/kg (3.6 x 1010 sp/kg) in 21 day dermal application and maximum attainable concentration of dust aerosol 18mg/m3 (2.2 x 108 sp/m3) during a 30 day inhalation exposure are "no toxic effect" levels. On the basis of these data, Bulmoscide has been determined to be of low toxicity, presenting little hazard in terms of the Hygiene Classification of pesticides.
||toxic effects; bacteria; pesticides; inhalation toxicity; toxicity evaluation; dermal toxicity; biological insecticides
||Bulgaria; animal experiments; toxic substances
||D - Periodical articles
|Country / State or Province||Bulgaria|
||Toxic and dangerous substances
|Broad subject area(s)