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CISDOC database

Document ID (ISN)61111
CIS number 93-1973
ISBN(s) 92-4-157146-2
Year 1993
Convention or series no. Environmental Health Criteria 146
Author(s)
International Programme on Chemical Safety (IPCS)
Title 1,3-Dichloropropene, 1,2-dichloropropane and mixtures
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1993. 261p. ca. 350 ref. Price: CHF 31.00 (CHF 21.70 in developing countries).
Abstract Occupational exposure to 1,3-dichloropropene and 1,2-dichloropropane may be through inhalation or via the skin. 1,3-dichloropropene causes irritation of the eyes and the upper respiratory mucosa. Inhalation of high concentrations results in serious signs and symptoms of poisoning, while lower exposures result in depression of the central nervous system and irritation of the respiratory system. Dermal exposure causes severe skin irritation. Liver and kidney function changes have also been reported. Several cases of dermatitis and skin sensitisation have been reported in workers using solvent mixtures containing 1,2-dichloropropane. Detailed summaries in French and Spanish.
Descriptors (primary) agricultural chemicals; IPCS; propylene dichloride; agriculture; toxicology; toxicity evaluation; dichloropropene
Descriptors (secondary) toxic effects; neurotoxic effects; literature survey; irritants; ILO; UNEP; criteria document; renal dysfunction; skin absorption; hepatic disorders; dermatitis; toxic substances; sensitizers; WHO
Document type E - Books, reports, proceedings
Country / State or ProvinceWHO
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals
Halogenated hydrocarbons
Agriculture