| Document ID (ISN) | 60994 |
| CIS number |
93-1676 |
| ISBN(s) |
91-7045-195-8 |
| Year |
1992 |
| Convention or series no. |
Arbete och hälsa 1992:43
|
| Author(s) |
Skerfving S. |
| Title |
Nordic Expert Group for the Documentation of Exposure Limits. 104. Inorganic lead |
| Original title |
Nordiska Expertgruppen för Gränsvärdesdokumentation. 104. Oorganiskt bly [in Swedish] |
| Bibliographic information |
Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1992. 111p. Illus. 897 ref. |
| Abstract |
Review and evaluation of the relevant literature. Lead is present in the environment, and additional exposure may occur in many industrial settings. Its metabolism is adequately described by a two-compartment model: lead in soft tissues has a half-life of about one month and the bone lead pool has a half-life of about 10 years. The whole-blood level (B-Pb) is the most valuable tool for biological monitoring. Basal levels are highly variable, but average about 0.4µmol/L in the Nordic countries. Effects on the nervous system and kidneys are critical for the establishment of exposure limits. Sensitive adults show effects at exposure corresponding to B-Pbs of 1.5-2.0µmol/L, and foetuses may suffer non-specific central nervous system effects at maternal B-Pbs of 0.5-0.75µmol/L. |
| Descriptors (primary) |
Nordic Countries; renal dysfunction; determination of exposure limits; diseases of nervous system; lead and compounds |
| Descriptors (secondary) |
literature survey; criteria document; lead |
| Document type |
F - Information notes, codes of practice, standards |
| Country / State or Province | Sweden |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Diseases of the kidney and the urinary system
Lead and compounds
|
