|Document ID (ISN)||60589|
|ISSN - Serial title
||1775-8785 - Archives des maladies professionnelles
|Convention or series no.
||Guindo Nignan M., Garnier R., Telolahy P., Auger J., Ditcharles D., Dossier E., Klein E., Nguyen-Auvier D., Renault B.
||Urinary concentrations of inorganic arsenic, methylarsonic acid and dimethylarsinic acid in workers engaged in the production of gallium arsenide semi-conductors
||Excrétion urinaire d'arsenic minéral, d'acide méthylarsonique et d'acide diméthylarsinique lors de la fabrication de micro-composants sur substrat d'arséniure de gallium [in French]|
||1992, Vol.53, No.5, p.375-381. Illus. 33 ref.
||The determination of urinary concentrations of inorganic arsenic methylarsonic acid (M.A.A.) and dimethylarsinic acid (D.M.A.) through direct hydride generation from urine is an easy, inexpensive and reliable method for the biological monitoring of workers exposed to inorganic arsenic. This method was used for the biological monitoring of 79 workers engaged in the manufacturing of gallium arsenide semi-conductors in 7 different plants. 238 urine samples were obtained. The results presented are in agreement with those of two similar studies of smaller groups of gallium arsenide-exposed workers. Increases in urinary inorganic arsenic, methylarsonic acid and dimethylarsinic acid concentrations were rare and always small. The mean total urinary arsenic concentration was low (<20µg/g creatinine); more than 90% of all measurements were consistent with dietary-only arsenic absorption; no-one showed inorganic arsenic absorption corresponding to an 8h TWA of 100µg/m3 or more (i.e. half the French TLV).
||arsenic acid; gallium arsenide; methylarsonic acid; exposure tests; determination in urine; inorganic acids
||semiconductor devices; exposure; sampling and analysis; epidemiologic study
||D - Periodical articles
|Country / State or Province||France|
||Toxic and dangerous substances
|Broad subject area(s)
||Occupational medicine, epidemiology
Arsenic and compounds