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Document ID (ISN)60366
CIS number 93-1008
ISSN - Serial title 0140-6736 - Lancet
Year 1993
Convention or series no.
Author(s) Tomášek L., Darby S.C., Swerdlow A.J., Plaček V., Kunz E.
Title Radon exposure and cancers other than lung cancer among uranium miners in West Bohemia
Bibliographic information 10 Apr. 1993, Vol.341, No.8850, p.919-923. 30 ref.
Abstract Report on a site-specific cancer mortality study of 4,320 uranium miners in Western Bohemia (Czech Republic), who have been followed up for an average of 25 years, and among whom a 4-fold radon-related excess of lung cancer had already been established. For all cancers other than lung cancer the number of deaths was slightly greater than expected from national rates, but the increase was not statistically significant (O/E 1.11, 95% CI=0.98-1.24). There was no relationship between mortality on one hand, and duration of employment underground and cumulative radon (Rn) exposure on the other. There was a significant increase (unrelated to cumulative Rn exposure) in non-lung cancer mortality among men who started mining work aged under 25. Of the 28 site-specific cancers examined, significant increases were found for cancers of the liver (O/E=1.67) and gallbladder and extrahepatic bileducts (O/E=2.26, related to cumulative Rn exposure). There were no significant increases in overall mortality from multiple myeloma (O/E=1.08) and leukaemia (O/E=0.91), but mortality from these causes increased with cumulative Rn exposure and increased employment duration, respectively. Further research is needed to confirm any association between Rn exposure and cancers other than lung cancer.
Descriptors (primary) Czech Republic; radon; neoplasms; mortality; uranium mining; particulate radiation
Descriptors (secondary) leukaemia; occupation disease relation; myeloma; liver cancer; gallbladder diseases; length of service; lung cancer
Document type D - Periodical articles
Country / State or ProvinceCzech Republic; United Kingdom
Subject(s) Radiation
Broad subject area(s) Physical hazards
Browse category(ies) Radon
Mining and quarrying
Inorganic substances
Ionizing radiation