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CISDOC database

Document ID (ISN)60057
CIS number 93-910
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1992
Convention or series no.
Author(s) Linz D.H., Barrett E.T., Pflaumer J.E., Keith R.E.
Title Neuropsychologic and postural sway improvement after Ca++-EDTA chelation for mild lead intoxication
Bibliographic information June 1992, Vol.34, No.6, p.638-641. 16 ref.
Abstract The case study reports a bridge worker with chronic lead intoxication and borderline whole body lead burden who showed dramatic improvement in postural stability and neuropsychological functioning shortly after a single five-day course of intravenous Ca++-EDTA (calcium disodium ethylenediaminetetraacetic acid) as a chelating agent. This case highlights the value of neurobehavioural and postural stability testing in verifying symptoms and documenting response to therapy. The improvement after chelation suggests that central nervous system symptomatology may be reversed in adult patients even when total body lead burden is modest.
Descriptors (primary) poisoning; medical treatment; long-term exposure; lead
Descriptors (secondary) case study; symptoms; chelation therapy; perceptual-motor performance tests; balance tests; psychological tests
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Lead and compounds
Inorganic substances