| Document ID (ISN) | 59706 |
| CIS number |
93-545 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Rom W.N. |
| Title |
Accelerated loss of lung function and alveolitis in a longitudinal study of non-smoking individuals with occupational exposure to asbestos |
| Bibliographic information |
June 1992, Vol.21, No.6, p.835-844. Illus. 38 ref. |
| Abstract |
77 long-term asbestos workers engaged in the insulation of pipes and boilers were evaluated to quantitate annual loss of lung function. All of them had chest X-rays ≥1/0 ILO category and were life-long non-smokers or ex-smokers for > 5 years. Study parameters included pulmonary function tests and bronchoalveolar lavage for a mean of 3 visits over 30 ± 2 months. Multiple regression analysis revealed significant associations between rales or radiographic opacities and VC, FEV1, and total lung capacity; significant associations were also found between neutrophils/mL lavage fluid with FEV1 and diffusing capacity (all p<0.05). Annual declines for the asbestos-exposed were VC -92±28mL/yr and FEV1 -66±21mL/yr. Compared to other asbestos-exposed cohorts followed longitudinally, asbestos insulators with radiographs ≥1/0 and exposure ≥20 years have higher rates of FVC and FEV1 decline for both non-smokers and ex-smokers. |
| Descriptors (primary) |
asbestos; functional respiratory disorders; respiratory impairment; exposure evaluation; respiratory function tests; insulating work |
| Descriptors (secondary) |
ILO; chest radiography; epidemiologic study |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Surface treatment
Exposure evaluation
Diseases of the respiratory system (except for pneumoconiosis & similar)
Asbestos
|
