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CISDOC database

Document ID (ISN)59672
CIS number 93-552
ISSN - Serial title 0140-6736 - Lancet
Year 1992
Convention or series no.
Author(s) Ward J.B., Ammenheuser M.M., Legator M.S.
Title Carcinogenicity of 1,3-butadiene
Bibliographic information 31 Oct. 1992, Vol.340, No.8827, p.1104. 6 ref.
Abstract A letter in response to an earlier one from Melnick et al (see CIS 92-1966) concerning evidence for the carcinogenicity of butadiene in humans. Studies reported here indicate that the present proposed exposure limit of 2ppm may not be sufficiently low to protect workers from health risks associated with butadiene exposure. Epidemiologic studies reported elsewhere link butadiene exposure with haemopoietic cancer.
Descriptors (primary) carcinogens; toxicity evaluation; butadiene
Descriptors (secondary) limitation of exposure; animal experiments; carcinogenic effects; metabolic studies; extrapolation animal man
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aliphatic and alicyclic hydrocarbons