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CISDOC database

Document ID (ISN)59452
CIS number 93-222
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1992
Convention or series no.
Author(s) Bond G.G., Bodner K.M., Olsen G.W., Cook R.R.
Title Mortality among workers engaged in the development or manufacture of styrene-based products - An update
Bibliographic information June 1992, Vol.18, No.3, p.145-154. 23 ref.
Abstract Mortality data were updated another 11 years through 1986 for a previously studied cohort of 2,904 male chemical workers who had been potentially exposed to styrene and related materials for a year or more between 1937 and 1971. Substantial deficits in mortality from all causes and from all cancers were observed in the cohort when it was compared with white males in the United States, and with other chemical workers who were unexposed to styrene-based products. Mortality from leukaemia was slightly less than expected, in contrast to an excess of lymphatic leukaemia observed in the original period. Yet small elevations in risk of other types of lymphatic cancer, particularly multiple myeloma, persisted. The risk of these cancers did not increase with estimated intensity or duration of styrene exposure. The findings are discussed in context with those of studies of similarly exposed workers in related industries.
Descriptors (primary) carcinogens; chemical industry; neoplasms; mortality; carcinogenic effects; styrene
Descriptors (secondary) lymphatic leukaemia; benzene; butadiene; comparative study; myeloma; long-term study; acrylonitrile
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Chemical industry
Aromatic hydrocarbons