| Document ID (ISN) | 59243 |
| CIS number |
92-1983 |
| ISSN - Serial title |
0867-8383 - Polish Journal of Occupational Medicine and Environmental Health |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Indulski J.A., Lutz W. |
| Title |
Biological monitoring of risk of bladder cancer in persons occupationally exposed to aromatic amines |
| Bibliographic information |
1992, Vol.5, No.2, p.143-151. 51 ref. |
| Abstract |
Recent advances in molecular biology and toxicology have greatly contributed to the early detection of biological changes associated with neoplasms. This paper reviews the issues regarding the screening of persons occupationally exposed to carcinogenic aromatic amines. The screening was designed for an early detection of bladder cancer by means of biochemical tests. The tests applied facilitated the estimation of the level of aromatic amines penetrating an organism (biomarkers of exposure), early diagnosis of the biochemical disorders which may influence cancer development (biomarkers of early effects) and the detection of genetic predispositions which enhance the risk of such disorders (biomarkers of susceptibility). |
| Descriptors (primary) |
aromatic amines; risk factors; bladder tumour; early diagnosis |
| Descriptors (secondary) |
carcinogenic effects; neoplasms; biochemical tests |
| Document type |
D - Periodical articles |
| Country / State or Province | Poland |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Diseases of the kidney and the urinary system
Aromatic amines
|
