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CISDOC database

Document ID (ISN)59116
CIS number 92-1966
ISSN - Serial title 0140-6736 - Lancet
Year 1992
Convention or series no.
Author(s) Melnick R.L., Huff J., Matanoski G.M.
Title Carcinogenicity of 1,3-butadiene
Bibliographic information 19 Sep. 1992, vol.340, No.8821, p.724-725. 9 ref.
Abstract This letter to the editor contends that carcinogenicity studies in laboratory animals provide a valuable means for predicting potential human risk. Data from animal experiments on the metabolism and carcinogenicity of butadiene are presented. Data available from previous epidemiological studies do not provide an appropriate evaluation of butadiene risk; the proposed lowering of the occupational exposure standard for butadiene in the US from 1000ppm to 2ppm is to be applauded.
Descriptors (primary) carcinogens; toxicity evaluation; butadiene
Descriptors (secondary) epidemiological aspects; carcinogenic effects; animal experiments
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aliphatic and alicyclic hydrocarbons