ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)59101
CIS number 92-1964
ISSN - Serial title 0960-3271 - Human and Experimental Toxicology
Year 1990
Convention or series no.
Author(s) McGregor A.J., Mason H.J.
Title Chronic occupational lead exposure and testicular endocrine function
Bibliographic information 1990, Vol.9, p.371-376. 16 ref.
Abstract Lead concentrations in blood and bone were measured as indices of short and long-term, cumulative exposure in a group of 90 men occupationally exposed to inorganic lead. Results showed that the lead exposure levels encountered in the UK at present may result in a subclinical increase in follicle stimulating hormone (FSH) which is related to blood lead levels. This suggests that lead may be causing some subclinical primary damage to the seminiferous tubules in the testes. At blood lead levels of <47µg/dL this effect on serum FSH is not apparent.
Descriptors (primary) antifertility effects; spermatogenic disturbances; lead
Descriptors (secondary) hormones; determination in bones; determination in blood; endocrine effects
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the reproductive system
Antifertility and prenatal effects
Lead and compounds
Inorganic substances
Genetic factors in reaction to exposures