| Document ID (ISN) | 58905 |
| CIS number |
92-1718 |
| ISSN - Serial title |
0025-6749 - Médecine et hygiène |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Galanou I., Pécoud A. |
| Title |
Allergy to laboratory animals: Test interpretation versus diagnosis |
| Original title |
Allergie aux animaux de laboratoire: considérations diagnostiques [in French] |
| Bibliographic information |
2 Sep. 1992, Vol.50, No.1944, p.2121-2122, 2125-2126. |
| Abstract |
Allergy to laboratory animals occurs in 10-30% of subjects professionally exposed to rats, mice or rabbits. Results of diagnostic tests (skin tests, specific IgE in serum) performed with different allergens (epithelium, urine, serum) were analysed. Skin tests using commercial extracts were not consistently positive, in vitro tests tended to give more frequent positive results than did traditional RAST, and in general, it was sufficient for the identification of IgE to use animal epithelium (urine and serum are less useful). The Pharmacia CAP system gave positive results more frequently than traditional RAST. The positive results found in healthy subjects reinforce the need for a careful case history in interpreting allergological diagnostic tests. |
| Descriptors (primary) |
experimental animals; allergies; animal experiments; skin allergies; diagnosis; allergic asthma |
| Descriptors (secondary) |
anamnesis; comparative study; description of technique |
| Document type |
D - Periodical articles |
| Country / State or Province | Switzerland |
| Subject(s) |
Commerce, services, offices
|
| Broad subject area(s) |
Biological hazards
|
| Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar)
Animal hazards
Allergies
Skin diseases
|
