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Document ID (ISN)58817
CIS number 92-1535
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1991
Convention or series no.
Author(s) Partanen T., Heikkilä P., Hernberg S., Kauppinen T., Moneta G., Ojajärvi A.
Title Renal cell cancer and occupational exposure to chemical agents
Bibliographic information Aug. 1991, Vol.17, No.4, p.231-239. 47 ref.
Abstract A case-referent study of occupational risk indicators of renal cell adenocarcinoma was conducted. Each incident case in Finland in 1977-1978 was matched with two population referents. Lifelong job histories were collected and translated into indicators of industry, occupation, and occupational exposures. The analyses of 338 sets of cases and referents revealed elevated risks for a history of employment in: white-collar occupations; the printing industry; the chemical industry; the manufacture of metal products; mail, telephone, and telegraph services; metalworking. A decreased risk was observed for male farmers. An elevated risk and an exposure-response relationship were found for gasoline exposure. The excess risk was highest at a latency period of approximately 30 years. The findings support the hypothesis that exposure to some constituent(s) of gasoline increases the incidence of renal adenocarcinoma in humans. Suggestions of elevated risks appeared for exposures to inorganic lead, cadmium, and nonchlorinated solvents.
Descriptors (primary) lead; renal cancer; cadmium; solvents; carcinogenic effects; motor fuel
Descriptors (secondary) Finland; multifactor aetiology; comparative study; hazard evaluation; questionnaire survey; latency
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the kidney and the urinary system
Lead and compounds
Cadmium and compounds
Inorganic substances