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Document ID (ISN)58805
CIS number 92-1530
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1991
Convention or series no.
Author(s) Fatma N., Jain A.K., Rahman Q.
Title Frequency of sister chromatid exchange and chromosomal aberrations in asbestos cement workers
Bibliographic information Feb. 1991, Vol.48, No.2, p.103-105. 11 ref.
Abstract Exposure to asbestos minerals has been associated with a wide variety of adverse health effects including lung cancer, pleural mesothelioma, and cancer of other organs. Twenty-two workers from an asbestos cement factory and 12 controls were investigated. Controls were matched for age, sex, and socioeconomic status. Peripheral blood lymphocytes were cultured and harvested at 48h for studies of chromosomal aberrations and at 72h for SCE frequency determinations. Asbestos workers had a higher mean SCE rate and increased numbers of chromosomal aberrations. Most of the chromosomal aberrations were chromatid gap and break types.
Descriptors (primary) asbestos; asbestos cement industry; chromosome changes; respirable dust
Descriptors (secondary) cytogenetic studies; comparative study; frequency rates; analysis of chromosome aberrations
Document type D - Periodical articles
Country / State or ProvinceIndia
Subject(s) Dust, aerosols and related diseases
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Cement and concrete
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Asbestos