| Document ID (ISN) | 58418 |
| CIS number |
92-1257 |
| ISSN - Serial title |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
| Year |
1991 |
| Convention or series no. |
|
| Author(s) |
Lindbohm M.L., Sallmén M., Anttila A., Taskinen H., Hemminki K. |
| Title |
Paternal occupational lead exposure and spontaneous abortion |
| Bibliographic information |
Apr. 1991, Vol.17, No.2, p.95-103. Illus. 19 ref. |
| Abstract |
A case-referent study was conducted in order to find out if occupational exposure of men to inorganic lead is related to spontaneous abortion in their wives. The men were biologically monitored for lead exposure. The cases (213 spontaneous abortions) and referents (300 births) were identified from Finnish medical registers. Lead exposure was assessed with blood lead (PbB) measurements and data obtained from a questionnaire. The results did not show a statistically significant relationship between spontaneous abortion and paternal lead exposure among the study subjects. A significant increase was observed in the risk of those women whose husbands had been monitored (PbB ≥1.5µmol/L) during or close to the time of spermatogenesis. The association between lead exposure and spontaneous abortion was modified also by the age of the wife and paternal alcohol use. The findings suggest that there may be an association between paternal lead exposure and the risk of spontaneous abortion. |
| Descriptors (primary) |
lead; expectant mothers; genetic effects; abortion |
| Descriptors (secondary) |
exposure evaluation; comparative study; exposure tests; questionnaire survey |
| Document type |
D - Periodical articles |
| Country / State or Province | Finland |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Lead and compounds
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Diseases of the reproductive system
|
