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CISDOC database

Document ID (ISN)58418
CIS number 92-1257
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1991
Convention or series no.
Author(s) Lindbohm M.L., SallmÚn M., Anttila A., Taskinen H., Hemminki K.
Title Paternal occupational lead exposure and spontaneous abortion
Bibliographic information Apr. 1991, Vol.17, No.2, p.95-103. Illus. 19 ref.
Abstract A case-referent study was conducted in order to find out if occupational exposure of men to inorganic lead is related to spontaneous abortion in their wives. The men were biologically monitored for lead exposure. The cases (213 spontaneous abortions) and referents (300 births) were identified from Finnish medical registers. Lead exposure was assessed with blood lead (PbB) measurements and data obtained from a questionnaire. The results did not show a statistically significant relationship between spontaneous abortion and paternal lead exposure among the study subjects. A significant increase was observed in the risk of those women whose husbands had been monitored (PbB ≥1.5Ámol/L) during or close to the time of spermatogenesis. The association between lead exposure and spontaneous abortion was modified also by the age of the wife and paternal alcohol use. The findings suggest that there may be an association between paternal lead exposure and the risk of spontaneous abortion.
Descriptors (primary) lead; expectant mothers; genetic effects; abortion
Descriptors (secondary) exposure evaluation; comparative study; exposure tests; questionnaire survey
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the reproductive system
Antifertility and prenatal effects
Lead and compounds
Inorganic substances
Genetic factors in reaction to exposures