| Document ID (ISN) | 57967 |
| CIS number |
92-946 |
| Year |
1991 |
| Convention or series no. |
|
| Author(s) |
Deneauve-Lockhart C. |
| Title |
Acute yperite poisoning - An occupational accident |
| Original title |
Intoxication aiguë par l'ypérite. A propos d'un accident du travail [in French] |
| Bibliographic information |
Université Pierre et Marie Curie, UER Broussais Hôtel-Dieu, 15 rue de l'Ecole de Médecine, 75006 Paris, France, 1991. 25p. 19 ref. |
| Abstract |
Dissertation for a Diploma in Special Studies in occupational medicine. A case of yperite poisoning during ground clearing operations is described and the use of the gas in chemical warfare is reviewed. A study of its toxic mechanisms shows that this gas is an alkylating agent responsible for DNA modifications. Survey of some other cases of occupational poisoning, as well as of clinical effects, diagnosis, and treatment. Evidence of long term risk, including experimental mutagenic and carcinogenic data, and human genotoxic and epidemiological data, serves to classify yperite as a human carcinogen. Advice is given on the action to take in the case of occupational poisoning. |
| Descriptors (primary) |
carcinogens; building industry; construction sites; mustard gas |
| Descriptors (secondary) |
mutagenic effects; acute poisoning; genetic effects; thesis; accident descriptions |
| Document type |
E - Books, reports, proceedings |
| Country / State or Province | France |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Construction industry and civil engineering
Genetic factors in reaction to exposures
Organosulfur compounds
|
