| Document ID (ISN) | 57696 |
| CIS number |
92-544 |
| ISSN - Serial title |
0140-6736 - Lancet |
| Year |
1991 |
| Convention or series no. |
|
| Author(s) |
Manz A., Berger J., Dwyer J.H., Flesch-Janys D., Nagel S., Waltsgott H. |
| Title |
Cancer mortality among workers in chemical plant contaminated with dioxin |
| Bibliographic information |
19 Oct. 1991, Vol.338, No.8773, p.959-964. 30 ref. |
| Abstract |
Report of a follow-up study of 1,583 workers employed in a chemical plant in Germany producing herbicides where they might be exposed to processes using tetrachlorodibenzodioxin (TCDD). Production of TCDD was reduced from 1954 after an outbreak of chloracne. Cancer mortality was found to be increased among men with 20 or more years of employment, and among men who began employment before 1955. Only 7% of cohort women worked in the high exposure locations in the plant and no increased risk of cancer mortality was observed, although breast cancer mortality was raised. Results support the hypothesis that TCDD is a human carcinogen. |
| Descriptors (primary) |
chemical industry; Germany (Federal Republic of); neoplasms; mortality; tetrachlorodibenzodioxin |
| Descriptors (secondary) |
carcinogens; exposure evaluation; statistical evaluation; long-term study; epidemiologic study |
| Document type |
D - Periodical articles |
| Country / State or Province | Germany; USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Heterocyclic compounds
Chemical industry
|
