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Document ID (ISN)57471
CIS number 92-246
ISBN(s) 92-4-157124-1
Year 1991
Convention or series no. Environmental Health Criteria 124
Author(s)
International Programme on Chemical Safety (IPCS)
Title Lindane
Bibliographic information World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1991. 208p. Bibl.ref. Price: CHF 23.00 (in developing countries: CHF 16.10).
Abstract Notwithstanding extensive use over 40 years, very few cases of occupational poisoning due to lindane have been reported. In workers exposed for long periods during either manufacture or application of lindane, the only sign found was increased activity of drug-metabolising enzymes in the liver. There is no evidence for the relationship suggested in some publications between exposure to lindane and the occurrence of blood dyscrasias. Human studies indicate that a dose of approximately 1.0mg/kg body weight does not induce poisoning; however, a dose of 15-17mg/kg body weight resulted in severe toxic symptoms. Detailed summaries in French and Spanish.
Descriptors (primary) agricultural chemicals; IPCS; toxicity evaluation; toxicology; lindane
Descriptors (secondary) poisoning; literature survey; ILO; criteria document; WHO; pesticides; UNEP
Document type E - Books, reports, proceedings
Country / State or ProvinceWHO
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Halogenated hydrocarbons
Agricultural chemicals