|Document ID (ISN)||57471|
|Convention or series no.
||Environmental Health Criteria 124
International Programme on Chemical Safety (IPCS)
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1991. 208p. Bibl.ref. Price: CHF 23.00 (in developing countries: CHF 16.10).
||Notwithstanding extensive use over 40 years, very few cases of occupational poisoning due to lindane have been reported. In workers exposed for long periods during either manufacture or application of lindane, the only sign found was increased activity of drug-metabolising enzymes in the liver. There is no evidence for the relationship suggested in some publications between exposure to lindane and the occurrence of blood dyscrasias. Human studies indicate that a dose of approximately 1.0mg/kg body weight does not induce poisoning; however, a dose of 15-17mg/kg body weight resulted in severe toxic symptoms. Detailed summaries in French and Spanish.
||agricultural chemicals; IPCS; toxicity evaluation; toxicology; lindane
||poisoning; literature survey; ILO; criteria document; WHO; pesticides; UNEP
||E - Books, reports, proceedings
|Country / State or Province||WHO|
||Toxic and dangerous substances
|Broad subject area(s)