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CISDOC database

Document ID (ISN)57224
CIS number 92-119
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1990
Convention or series no.
Author(s) Hnizdo E., Baskind E., Sluis-Cremer G.K.
Title Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners
Bibliographic information Dec. 1990, Vol.16, No.6, p.411-422. Illus. 30 ref.
Abstract The combined effect of underground gold mining dust with a high content of free silica and tobacco smoking on the prevalence of respiratory impairment was examined among 2209 South African gold miners and 483 non-miners. The subjects were grouped as having normal function; minimal, moderate or marked obstruction; marked obstruction with restriction; or pure restriction on the basis of their lung function profiles. Each profile group was compared with the normal group for exposure prevalences, and additive and multiplicative relative risk models were applied to test for departure from the additivity of individual effects. Departure from additivity was found to increase progressively with the severity of obstructive impairment. The results indicated that approximately 94% of the cases with the most severe respiratory impairment (N=191) could have been prevented through the elimination of tobacco smoking. In conclusion, tobacco smoking was found to potentiate the effect of dust on respiratory impairments.
Descriptors (primary) silica; smoking; respiratory impairment; synergism; gold mining; respirable dust
Descriptors (secondary) South Africa; comparative study; respiratory function tests; underground work
Document type D - Periodical articles
Country / State or ProvinceSouth Africa
Subject(s) Dust, aerosols and related diseases
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying