|Document ID (ISN)||57224|
|ISSN - Serial title
||0355-3140 - Scandinavian Journal of Work, Environment and Health
|Convention or series no.
||Hnizdo E., Baskind E., Sluis-Cremer G.K.
||Combined effect of silica dust exposure and tobacco smoking on the prevalence of respiratory impairments among gold miners
||Dec. 1990, Vol.16, No.6, p.411-422. Illus. 30 ref.
||The combined effect of underground gold mining dust with a high content of free silica and tobacco smoking on the prevalence of respiratory impairment was examined among 2209 South African gold miners and 483 non-miners. The subjects were grouped as having normal function; minimal, moderate or marked obstruction; marked obstruction with restriction; or pure restriction on the basis of their lung function profiles. Each profile group was compared with the normal group for exposure prevalences, and additive and multiplicative relative risk models were applied to test for departure from the additivity of individual effects. Departure from additivity was found to increase progressively with the severity of obstructive impairment. The results indicated that approximately 94% of the cases with the most severe respiratory impairment (N=191) could have been prevented through the elimination of tobacco smoking. In conclusion, tobacco smoking was found to potentiate the effect of dust on respiratory impairments.
||silica; smoking; respiratory impairment; synergism; gold mining; respirable dust
||South Africa; comparative study; respiratory function tests; underground work
||D - Periodical articles
|Country / State or Province||South Africa|
||Dust, aerosols and related diseases
|Broad subject area(s)
||Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying